NAME THE GENETIC DISEASE IN WHICH MUTATIONS OF TWO (2) SEPARATE GENES (LAMC2 AND LAMA3) CAUSE AN IDENTICAL PHENOTYPE IN THE HORSE.

NAME THE GENETIC DISEASE IN WHICH MUTATIONS OF TWO (2) SEPARATE GENES (LAMC2 AND LAMA3) CAUSE AN IDENTICAL PHENOTYPE IN THE HORSE.1. Name the function of a Merkel cell. (1 mark) 2. Name the genetic disease in which mutations of two (2) separate genes (LAMC2 and LAMA3) cause an identical phenotype in the horse. (1 mark) 3. Name a major component of the outer plaque of the hemidesmosome. (1 mark) 4. Name an autoimmune disease associated with abnormalities of the outer plaque of the hemidesmosome in dogs. (1 mark) 5. Name the structural molecule associated with recessive dystrophic epidermolysis bullosa of Rotes Hohenvieh calves. (1 mark) 6. Name the gene associated with hereditary cutaneous mucinosis of the Chinese Shar pei. (1 mark) 7. State the mechanism by which copper deficiency leads to abnormalities in pigmentation in cattle. (1 mark) 8. Name the precursor of adrenocorticotropin hormone (ACTH) and melanocyte stimulating hormone (MSH). (1 mark) 9. Name the equine skin disease in which the cytokine thymic stromal lymphopoietin (TSLP) has been shown to be over expressed. (1 mark) Continued over page Veterinary Dermatology Paper 1 Page 3 of 7 © 2015 The Australian and New Zealand College of Veterinary Scientists ABN 00 50 000894 208 10. Name a molecular target of autoantibodies in human autoimmune urticaria. (1 mark) 11. Name a primary constituent of the cell wall of Pythium insidiosum. (1 mark) 12. Name the protein encoded by the ABCB1 (MDR1) gene. (1 mark) 13. State the primary function of Class 2 major histocompatibility complex (MHC) molecules. (1 mark) 14. Name the major anatomical location of collagen type VII. (1 mark) 15. Name a resident cutaneous cell that contains abundant vimentin. (1 mark) 16. Name the two (2) resident cutaneous cells dependent on stem cell factor for their embryologic development. (1 mark) 17. Name a major function of interleukin-5. (1 mark) 18. Name the major structural component of the layer of the dermo-epidermal junction known as the lamina densa. (1 mark) 19. Name the group of calcium dependent enzymes critical for formation of the cornified envelope. (1 mark) 20. Name the disease caused by mutations in the genes coding for keratins 5 and 14. (1 mark) Continued over page Veterinary Dermatology Paper 1 Page 4 of 7 © 2015 The Australian and New Zealand College of Veterinary Scientists ABN 00 50 000894 208 21. Name the antibody isotype that has a dimeric structure. (1 mark) 22. Name the step in the cholesterol to cortisol pathway catalysed by 3beta hydroxysteroid dehydrogenase. (1 mark) 23. Name one (1) commonly used proliferation marker in cutaneous veterinary oncology. (1 mark) 24. Name the Toll-like receptor that mediates the host response to gram positive bacteria. (1 mark) 25. Name three (3) techniques that have been reported for the demonstration of IgE responses to Malassezia pachydermatis in dogs. (1 mark) 26. Name the receptor on the keratinocyte surface which has been demonstrated to recognise chitin in the exoskeleton of Demodex canis. (1 mark) 27. Define the term ?cutaneous microbiome?. (1 mark) 28. Provide the term now used to describe hairless telogen. (1 mark) 29. Name the two (2) classes of antimicrobial peptides that are synthesised by inflammatory cells and epithelial surfaces. (1 mark) . US TODAY AND GET AN AMAZING DISCOUNT The post NAME THE GENETIC DISEASE IN WHICH MUTATIONS OF TWO (2) SEPARATE GENES (LAMC2 AND LAMA3) CAUSE AN IDENTICAL PHENOTYPE IN THE HORSE. appeared first on Nursing Homeworks.