1.Elaborate on the trend of interoperability of health care management information systems. Determine a significant challenge that health care organizations will face when creating anAugust 4, 2020/in Health and Mendical /by Joseph1.Elaborate on the trend of interoperability of health care management information systems. Determine a significant challenge that health care organizations will face when creating an interoperable system. Justify your response.2.Suggest a significant benefit of interoperability that is the result of the SAPHIRE project. Provide support for your rationale.3.Determine the most significant requirement of an effective solution to interoperability. Provide a rationale for your determination.4. Suggest a significant challenge of applying WSIHS to health care management information systems (HMIS), and indicate how the challenge may be mitigated..